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Similar requirement for clathrin in EGF- and HGF- stimulated Akt phosphorylation
Receptor tyrosine kinases, such as the epidermal growth factor (EGF) receptor (EGFR) and Met lead to activation of intracellular signals including Akt, a critical regulator of cell survival, metabolism and proliferation. Upon binding their respective ligands, each of these receptors is recruited int...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951169/ https://www.ncbi.nlm.nih.gov/pubmed/27489582 http://dx.doi.org/10.1080/19420889.2016.1175696 |