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Similar requirement for clathrin in EGF- and HGF- stimulated Akt phosphorylation

Receptor tyrosine kinases, such as the epidermal growth factor (EGF) receptor (EGFR) and Met lead to activation of intracellular signals including Akt, a critical regulator of cell survival, metabolism and proliferation. Upon binding their respective ligands, each of these receptors is recruited int...

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Detalles Bibliográficos
Autores principales: Lucarelli, Stefanie, Pandey, Rohan, Judge, Gurjeet, Antonescu, Costin N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951169/
https://www.ncbi.nlm.nih.gov/pubmed/27489582
http://dx.doi.org/10.1080/19420889.2016.1175696