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Deciphering the roles of phosphoinositide lipids in phagolysosome biogenesis

Professional phagocytes engulf microbial invaders into plasma membrane-derived phagosomes. These mature into microbicidal phagolysosomes, leading to killing of the ingested microbe. Phagosome maturation involves sequential fusion of the phagosome with early endosomes, late endosomes, and the main de...

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Detalles Bibliográficos
Autores principales: Jeschke, Andreas, Haas, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951175/
https://www.ncbi.nlm.nih.gov/pubmed/27489580
http://dx.doi.org/10.1080/19420889.2016.1174798