Cargando…

Metabolic network rewiring of propionate flux compensates vitamin B12 deficiency in C. elegans

Metabolic network rewiring is the rerouting of metabolism through the use of alternate enzymes to adjust pathway flux and accomplish specific anabolic or catabolic objectives. Here, we report the first characterization of two parallel pathways for the breakdown of the short chain fatty acid propiona...

Descripción completa

Detalles Bibliográficos
Autores principales: Watson, Emma, Olin-Sandoval, Viridiana, Hoy, Michael J, Li, Chi-Hua, Louisse, Timo, Yao, Victoria, Mori, Akihiro, Holdorf, Amy D, Troyanskaya, Olga G, Ralser, Markus, Walhout, Albertha JM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951191/
https://www.ncbi.nlm.nih.gov/pubmed/27383050
http://dx.doi.org/10.7554/eLife.17670