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Metabolic network rewiring of propionate flux compensates vitamin B12 deficiency in C. elegans
Metabolic network rewiring is the rerouting of metabolism through the use of alternate enzymes to adjust pathway flux and accomplish specific anabolic or catabolic objectives. Here, we report the first characterization of two parallel pathways for the breakdown of the short chain fatty acid propiona...
Autores principales: | Watson, Emma, Olin-Sandoval, Viridiana, Hoy, Michael J, Li, Chi-Hua, Louisse, Timo, Yao, Victoria, Mori, Akihiro, Holdorf, Amy D, Troyanskaya, Olga G, Ralser, Markus, Walhout, Albertha JM |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951191/ https://www.ncbi.nlm.nih.gov/pubmed/27383050 http://dx.doi.org/10.7554/eLife.17670 |
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