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Nickel chloride (NiCl(2)) induces endoplasmic reticulum (ER) stress by activating UPR pathways in the kidney of broiler chickens

It has been known that overexposure to Ni can induce nephrotoxicity. However, the mechanisms of underlying Ni nephrotoxicity are still elusive, and also Ni- and Ni compound-induced ER stress has been not reported in vivo at present. Our aim was to use broiler chickens as animal model to test whether...

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Detalles Bibliográficos
Autores principales: Guo, Hongrui, Cui, Hengmin, Peng, Xi, Fang, Jing, Zuo, Zhicai, Deng, Junliang, Wang, Xun, Wu, Bangyuan, Chen, Kejie, Deng, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951229/
https://www.ncbi.nlm.nih.gov/pubmed/26956054
http://dx.doi.org/10.18632/oncotarget.7919