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DDRI-9: a novel DNA damage response inhibitor that blocks mitotic progression

The DNA damage response (DDR) is an emerging target for cancer therapy. By modulating the DDR, including DNA repair and cell cycle arrest, the efficacy of anticancer drugs can be enhanced and side effects reduced. We previously screened a chemical library and identified novel DDR inhibitors includin...

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Detalles Bibliográficos
Autores principales: Jun, Dong Wha, Hwang, Mihwa, Kim, Yun-Hee, Kim, Kyung-Tae, Kim, Sunshin, Lee, Chang-Hun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951243/
https://www.ncbi.nlm.nih.gov/pubmed/26848527
http://dx.doi.org/10.18632/oncotarget.7135