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EF24 induces ROS-mediated apoptosis via targeting thioredoxin reductase 1 in gastric cancer cells

Gastric cancer (GC) is one of the leading causes of cancer mortality in the world, and finding novel agents for the treatment of advanced gastric cancer is of urgent need. Diphenyl difluoroketone (EF24), a molecule having structural similarity to curcumin, exhibits potent anti-tumor activities by ar...

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Detalles Bibliográficos
Autores principales: Zou, Peng, Xia, Yiqun, Chen, Weiqian, Chen, Xi, Ying, Shilong, Feng, Zhiguo, Chen, Tongke, Ye, Qingqing, Wang, Zhe, Qiu, Chenyu, Yang, Shulin, Liang, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951270/
https://www.ncbi.nlm.nih.gov/pubmed/26919110
http://dx.doi.org/10.18632/oncotarget.7633