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Mitotic cell death caused by follistatin-like 1 inhibition is associated with up-regulated Bim by inactivated Erk1/2 in human lung cancer cells

Follistatin-like 1 (FSTL1) was identified as a novel pro-inflammatory protein showing high-level expression in rheumatoid arthritis. The protective effect of FSTL1 via the inhibition of apoptosis was reported in myocardial injury. However, the functional mechanism of FSTL1 in cancer is poorly charac...

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Detalles Bibliográficos
Autores principales: Bae, Kieun, Park, Kyoung Eun, Han, Jihye, Kim, Jongkwang, Kim, Kyungtae, Yoon, Kyong-Ah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951272/
https://www.ncbi.nlm.nih.gov/pubmed/26716515
http://dx.doi.org/10.18632/oncotarget.6729