Targeting the insulin growth factor-1 receptor with fluorescent antibodies enables high resolution imaging of human pancreatic cancer in orthotopic mouse models

The goal of the present study was to determine whether insulin-like growth factor-1 receptor (IGF-1R) antibodies, conjugated with bright fluorophores, could enable visualization of pancreatic cancer in orthotopic nude mouse models. IGF-1R antibody (clone 24-31) was conjugated with 550 nm or 650 nm f...

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Detalles Bibliográficos
Autores principales: Park, Jeong Youp, Lee, Jin Young, Zhang, Yong, Hoffman, Robert M., Bouvet, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951286/
https://www.ncbi.nlm.nih.gov/pubmed/26919100
http://dx.doi.org/10.18632/oncotarget.7576

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951286/
https://www.ncbi.nlm.nih.gov/pubmed/26919100
http://dx.doi.org/10.18632/oncotarget.7576

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