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Targeting the insulin growth factor-1 receptor with fluorescent antibodies enables high resolution imaging of human pancreatic cancer in orthotopic mouse models
The goal of the present study was to determine whether insulin-like growth factor-1 receptor (IGF-1R) antibodies, conjugated with bright fluorophores, could enable visualization of pancreatic cancer in orthotopic nude mouse models. IGF-1R antibody (clone 24-31) was conjugated with 550 nm or 650 nm f...
Autores principales: | Park, Jeong Youp, Lee, Jin Young, Zhang, Yong, Hoffman, Robert M., Bouvet, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951286/ https://www.ncbi.nlm.nih.gov/pubmed/26919100 http://dx.doi.org/10.18632/oncotarget.7576 |
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