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miR-342 overexpression results in a synthetic lethal phenotype in BRCA1-mutant HCC1937 breast cancer cells

Expression of miR-342 has been strongly correlated with estrogen receptor (ER) status in breast cancer, where it is highest in ER-positive and lowest in triple-negative tumors. We investigated the effects of miR-342 transfection in the triple-negative breast cancer cell lines MDA-MB-231 and HCC1937,...

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Detalles Bibliográficos
Autores principales: Crippa, Elisabetta, Folini, Marco, Pennati, Marzia, Zaffaroni, Nadia, Pierotti, Marco A., Gariboldi, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951312/
https://www.ncbi.nlm.nih.gov/pubmed/26919240
http://dx.doi.org/10.18632/oncotarget.7617