microRNAs are differentially regulated between MDM2-positive and negative malignant pleural mesothelioma

BACKGROUND: Malignant pleural mesothelioma (MPM) is a highly aggressive tumour first-line treated with a combination of cisplatin and pemetrexed. MDM2 and P14/ARF (CDKN2A) are upstream regulators of TP53 and may contribute to its inactivation. In the present study, we now aimed to define the impact...

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Detalles Bibliográficos
Autores principales: Walter, Robert Fred Henry, Vollbrecht, Claudia, Werner, Robert, Wohlschlaeger, Jeremias, Christoph, Daniel Christian, Schmid, Kurt Werner, Mairinger, Fabian Dominik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951323/
https://www.ncbi.nlm.nih.gov/pubmed/26918730
http://dx.doi.org/10.18632/oncotarget.7666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951323/
https://www.ncbi.nlm.nih.gov/pubmed/26918730
http://dx.doi.org/10.18632/oncotarget.7666

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