Androgen receptor in Sertoli cells regulates DNA double-strand break repair and chromosomal synapsis of spermatocytes partially through intercellular EGF-EGFR signaling

Spermatogenesis does not progress beyond the pachytene stages of meiosis in Sertoli cell-specific AR knockout (SCARKO) mice. However, further evidence of meiotic arrest and underlying paracrine signals in SCARKO testes is still lacking. We utilized co-immunostaining of meiotic surface spreads to exa...

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Detalles Bibliográficos
Autores principales: Chen, Su-Ren, Hao, Xiao-Xia, Zhang, Yan, Deng, Shou-Long, Wang, Zhi-Peng, Wang, Yu-Qian, Wang, Xiu-Xia, Liu, Yi-Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951324/
https://www.ncbi.nlm.nih.gov/pubmed/26959739
http://dx.doi.org/10.18632/oncotarget.7916

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951324/
https://www.ncbi.nlm.nih.gov/pubmed/26959739
http://dx.doi.org/10.18632/oncotarget.7916

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