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CtBP1 associates metabolic syndrome and breast carcinogenesis targeting multiple miRNAs

Metabolic syndrome (MeS) has been identified as a risk factor for breast cancer. C-terminal binding protein 1 (CtBP1) is a co-repressor of tumor suppressor genes that is activated by low NAD+/NADH ratio. High fat diet (HFD) increases intracellular NADH. We investigated the effect of CtBP1 hyperactiv...

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Detalles Bibliográficos
Autores principales: De Luca, Paola, Dalton, Guillermo N., Scalise, Georgina D., Moiola, Cristian P., Porretti, Juliana, Massillo, Cintia, Kordon, Edith, Gardner, Kevin, Zalazar, Florencia, Flumian, Carolina, Todaro, Laura, Vazquez, Elba S., Meiss, Roberto, De Siervi, Adriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951330/
https://www.ncbi.nlm.nih.gov/pubmed/26933806
http://dx.doi.org/10.18632/oncotarget.7711