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CXCR4/CXCL12/CXCR7 axis is functional in neuroendocrine tumors and signals on mTOR

OBJECTIVE: To evaluate the possible crosstalk between C-X-C chemokine receptor 4 (CXCR4)/C-X-C motif chemokine 12 (CXCL12)/C-X-C chemokine receptor 7 (CXCR7) axis with the mammalian target of rapamycin (mTOR) pathway in neuroendocrine tumors (NETs). METHODS: Sixty-one human NETs were included into t...

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Detalles Bibliográficos
Autores principales: Circelli, Luisa, Sciammarella, Concetta, Guadagno, Elia, Tafuto, Salvatore, del Basso de Caro, Marialaura, Botti, Giovanni, Pezzullo, Luciano, Aria, Massimo, Ramundo, Valeria, Tatangelo, Fabiana, Losito, Nunzia Simona, Ieranò, Caterina, D'Alterio, Crescenzo, Izzo, Francesco, Ciliberto, Gennaro, Colao, Annamaria, Faggiano, Antongiulio, Scala, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951335/
https://www.ncbi.nlm.nih.gov/pubmed/26934559
http://dx.doi.org/10.18632/oncotarget.7738