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Susceptibility to Aspergillus Infections in Rats with Chronic Obstructive Pulmonary Disease via Deficiency Function of Alveolar Macrophages and Impaired Activation of TLR2

Clinical evidence indicates that patients with severe chronic obstructive pulmonary disease (COPD) are more susceptible to Aspergillus. However, the exact mechanisms underlying this effect are not known. In this study, we used cigarette smoke exposure to generate COPD rat model. colony-forming units...

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Detalles Bibliográficos
Autores principales: Wu, Yuting, Xu, Hong, Li, Li, Yuan, Weifeng, Zhang, Deming, Huang, Wenjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951508/
https://www.ncbi.nlm.nih.gov/pubmed/27312383
http://dx.doi.org/10.1007/s10753-016-0363-x