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G protein-coupled estrogen receptor inhibits the P2Y receptor-mediated Ca(2+) signaling pathway in human airway epithelia

P2Y receptor activation causes the release of inflammatory cytokines in the bronchial epithelium, whereas G protein-coupled estrogen receptor (GPER), a novel estrogen (E(2)) receptor, may play an anti-inflammatory role in this process. We investigated the cellular mechanisms underlying the inhibitor...

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Detalles Bibliográficos
Autores principales: Hao, Yuan, Chow, Alison W., Yip, Wallace C., Li, Chi H., Wan, Tai F., Tong, Benjamin C., Cheung, King H., Chan, Wood Y., Chen, Yangchao, Cheng, Christopher H., Ko, Wing H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951515/
https://www.ncbi.nlm.nih.gov/pubmed/27271044
http://dx.doi.org/10.1007/s00424-016-1840-7