Cargando…
Folate-conjugated polyspermine for lung cancer–targeted gene therapy
Biodegradable polyamines have long been studied as potential recombinant viral gene vectors. Spermine (SPE) is an endogenous tetra-amine with excellent biocompatibility yet poor gene condensation capacity. We have previously synthesized a polyspermine based on SPE and poly(ethylene glycol) (PEG) dia...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951589/ https://www.ncbi.nlm.nih.gov/pubmed/27471674 http://dx.doi.org/10.1016/j.apsb.2016.03.010 |