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Folate-conjugated polyspermine for lung cancer–targeted gene therapy

Biodegradable polyamines have long been studied as potential recombinant viral gene vectors. Spermine (SPE) is an endogenous tetra-amine with excellent biocompatibility yet poor gene condensation capacity. We have previously synthesized a polyspermine based on SPE and poly(ethylene glycol) (PEG) dia...

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Detalles Bibliográficos
Autores principales:	Zhang, Mei, Kim, You-Kyoung, Cui, Pengfei, Zhang, Jialiang, Qiao, Jianbin, He, Yujing, Lyu, Jinyuan, Luo, Chengqiong, Xing, Lei, Jiang, Hulin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951589/ https://www.ncbi.nlm.nih.gov/pubmed/27471674 http://dx.doi.org/10.1016/j.apsb.2016.03.010

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