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The bacterial DNA repair protein Mfd confers resistance to the host nitrogen immune response

Production of reactive nitrogen species (NO) is a key step in the immune response following infections. NO induces lesions to bacterial DNA, thus limiting bacterial growth within hosts. Using two pathogenic bacteria, Bacillus cereus and Shigella flexneri, we show that the DNA-repair protein Mfd (Mut...

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Detalles Bibliográficos
Autores principales: Guillemet, Elisabeth, Leréec, Alain, Tran, Seav-Ly, Royer, Corinne, Barbosa, Isabelle, Sansonetti, Philippe, Lereclus, Didier, Ramarao, Nalini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951645/
https://www.ncbi.nlm.nih.gov/pubmed/27435260
http://dx.doi.org/10.1038/srep29349