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Poly(amino carbonate urethane)-based biodegradable, temperature and pH-sensitive injectable hydrogels for sustained human growth hormone delivery

In this study, a new pH-/temperature-sensitive, biocompatible, biodegradable, and injectable hydrogel based on poly(ethylene glycol)-poly(amino carbonate urethane) (PEG-PACU) copolymers has been developed for the sustained delivery of human growth hormone (hGH). In aqueous solutions, PEG-PACU-based...

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Detalles Bibliográficos
Autores principales: Phan, V. H. Giang, Thambi, Thavasyappan, Duong, Huu Thuy Trang, Lee, Doo Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951706/
https://www.ncbi.nlm.nih.gov/pubmed/27436576
http://dx.doi.org/10.1038/srep29978