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Quantification of Somatic Chromosomal Rearrangements in Circulating Cell-Free DNA from Ovarian Cancers

Recently, the use of a liquid biopsy has shown promise in monitoring tumor burden. While point mutations have been extensively studied, chromosomal rearrangements have demonstrated greater tumor specificity. Such rearrangements can be identified in the tumor and subsequently detected in the plasma o...

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Detalles Bibliográficos
Autores principales: Harris, Faye R., Kovtun, Irina V., Smadbeck, James, Multinu, Francesco, Jatoi, Aminah, Kosari, Farhad, Kalli, Kimberly R., Murphy, Stephen J., Halling, Geoffrey C., Johnson, Sarah H., Liu, Minetta C., Mariani, Andrea, Vasmatzis, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951715/
https://www.ncbi.nlm.nih.gov/pubmed/27436510
http://dx.doi.org/10.1038/srep29831