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Quantification of Somatic Chromosomal Rearrangements in Circulating Cell-Free DNA from Ovarian Cancers
Recently, the use of a liquid biopsy has shown promise in monitoring tumor burden. While point mutations have been extensively studied, chromosomal rearrangements have demonstrated greater tumor specificity. Such rearrangements can be identified in the tumor and subsequently detected in the plasma o...
Autores principales: | Harris, Faye R., Kovtun, Irina V., Smadbeck, James, Multinu, Francesco, Jatoi, Aminah, Kosari, Farhad, Kalli, Kimberly R., Murphy, Stephen J., Halling, Geoffrey C., Johnson, Sarah H., Liu, Minetta C., Mariani, Andrea, Vasmatzis, George |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951715/ https://www.ncbi.nlm.nih.gov/pubmed/27436510 http://dx.doi.org/10.1038/srep29831 |
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