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Multiple G-quartet structures in pre-edited mRNAs suggest evolutionary driving force for RNA editing in trypanosomes

Mitochondrial transcript maturation in African trypanosomes requires a U-nucleotide specific RNA editing reaction. In its most extreme form hundreds of U’s are inserted into and deleted from primary transcripts to generate functional mRNAs. Unfortunately, both origin and biological role of the proce...

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Detalles Bibliográficos
Autores principales: Leeder, W.-Matthias, Hummel, Niklas F. C., Göringer, H. Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951716/
https://www.ncbi.nlm.nih.gov/pubmed/27436151
http://dx.doi.org/10.1038/srep29810