Myeloid Deletion of Nemo Causes Osteopetrosis in Mice Owing to Upregulation of Transcriptional Repressors

The transcription factor NF-κB is central to numerous physiologic processes including bone development, and its activation is controlled by IKKγ (also called NEMO), the regulatory subunit of IKK complex. NEMO is X-linked, and mutations in this gene result in Incontinentia Pigmenti in human hemizygou...

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Detalles Bibliográficos
Autores principales: Swarnkar, Gaurav, Shim, Kyuhwan, Nasir, Amjad M., Seehra, Kuljeet, Chen, Hung-Po (Tim), Mbalaviele, Gabriel, Abu-Amer, Yousef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951754/
https://www.ncbi.nlm.nih.gov/pubmed/27435916
http://dx.doi.org/10.1038/srep29896

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951754/
https://www.ncbi.nlm.nih.gov/pubmed/27435916
http://dx.doi.org/10.1038/srep29896

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