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Efficient second-harmonic imaging of collagen in histological slides using Bessel beam excitation

Second-harmonic generation (SHG) is the most specific label-free indicator of collagen accumulation in widespread pathologies such as fibrosis, and SHG-based measurements hold important potential for biomedical analyses. However, efficient collagen SHG scoring in histological slides is hampered by t...

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Detalles Bibliográficos
Autores principales: Vuillemin, Nelly, Mahou, Pierre, Débarre, Delphine, Gacoin, Thierry, Tharaux, Pierre-Louis, Schanne-Klein, Marie-Claire, Supatto, Willy, Beaurepaire, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951755/
https://www.ncbi.nlm.nih.gov/pubmed/27435390
http://dx.doi.org/10.1038/srep29863