Chronic administration of aripiprazole activates GSK3β-dependent signalling pathways, and up-regulates GABA(A) receptor expression and CREB1 activity in rats

Aripiprazole is a D(2)-like receptor (D(2)R) partial agonist with a favourable clinical profile. Previous investigations indicated that acute and short-term administration of aripiprazole had effects on PKA activity, GSK3β-dependent pathways, GABA(A) receptors, NMDA receptor and CREB1 in the brain....

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Detalles Bibliográficos
Autores principales: Pan, Bo, Huang, Xu-Feng, Deng, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951756/
https://www.ncbi.nlm.nih.gov/pubmed/27435909
http://dx.doi.org/10.1038/srep30040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951756/
https://www.ncbi.nlm.nih.gov/pubmed/27435909
http://dx.doi.org/10.1038/srep30040

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