Cargando…
Chronic administration of aripiprazole activates GSK3β-dependent signalling pathways, and up-regulates GABA(A) receptor expression and CREB1 activity in rats
Aripiprazole is a D(2)-like receptor (D(2)R) partial agonist with a favourable clinical profile. Previous investigations indicated that acute and short-term administration of aripiprazole had effects on PKA activity, GSK3β-dependent pathways, GABA(A) receptors, NMDA receptor and CREB1 in the brain....
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951756/ https://www.ncbi.nlm.nih.gov/pubmed/27435909 http://dx.doi.org/10.1038/srep30040 |