Effect of Exendin-4 on Autophagy Clearance in Beta Cell of Rats with Tacrolimus-induced Diabetes Mellitus

Growing evidence suggests that GLP-1 protects beta cells against various cellular injuries by modulating autophagy. In this study, we examined whether exendin-4 (Ex-4), a GLP-1 analog, had preventive effects on tacrolimus (Tac)-induced beta cell injury by improving autophagy clearance. Rats with Tac...

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Detalles Bibliográficos
Autores principales: Lim, Sun Woo, Jin, Long, Jin, Jian, Yang, Chul Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951772/
https://www.ncbi.nlm.nih.gov/pubmed/27436514
http://dx.doi.org/10.1038/srep29921

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951772/
https://www.ncbi.nlm.nih.gov/pubmed/27436514
http://dx.doi.org/10.1038/srep29921

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