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Identification of baseline gene expression signatures predicting therapeutic responses to three biologic agents in rheumatoid arthritis: a retrospective observational study

BACKGROUND: According to EULAR recommendations, biologic DMARDs (bDMARDs) such as tumor necrosis factor inhibitor, tocilizumab (TCZ), and abatacept (ABT) are in parallel when prescribing to rheumatoid arthritis (RA) patients who have shown insufficient response to conventional synthetic DMARDs. Howe...

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Detalles Bibliográficos
Autores principales: Nakamura, Seiji, Suzuki, Katsuya, Iijima, Hiroshi, Hata, Yuko, Lim, Chun Ren, Ishizawa, Yohei, Kameda, Hideto, Amano, Koichi, Matsubara, Kenichi, Matoba, Ryo, Takeuchi, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4952232/
https://www.ncbi.nlm.nih.gov/pubmed/27435242
http://dx.doi.org/10.1186/s13075-016-1052-8