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Learning to Predict miRNA-mRNA Interactions from AGO CLIP Sequencing and CLASH Data

Recent technologies like AGO CLIP sequencing and CLASH enable direct transcriptome-wide identification of AGO binding and miRNA target sites, but the most widely used miRNA target prediction algorithms do not exploit these data. Here we use discriminative learning on AGO CLIP and CLASH interactions...

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Detalles Bibliográficos
Autores principales: Lu, Yuheng, Leslie, Christina S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954643/
https://www.ncbi.nlm.nih.gov/pubmed/27438777
http://dx.doi.org/10.1371/journal.pcbi.1005026