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A Functional rs353293 Polymorphism in the Promoter of miR-143/145 Is Associated with a Reduced Risk of Bladder Cancer

BACKGROUND AND OBJECTIVES: MicroRNA (miR)-143/145, known as tumor suppressors, can promote cell apoptosis and differentiation, and suppress cell proliferation, invasion and migration. We performed a case-control study to investigate the association of rs353293 in the promoter region of miR-143/145 w...

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Detalles Bibliográficos
Autores principales: Wu, Jun, Huang, Qun, Meng, Dongdong, Huang, Minyu, Li, Chaowen, Qin, Tianzi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954649/
https://www.ncbi.nlm.nih.gov/pubmed/27438131
http://dx.doi.org/10.1371/journal.pone.0159115