Efficient Inhibition of HIV Replication in the Gastrointestinal and Female Reproductive Tracts of Humanized BLT Mice by EFdA

BACKGROUND: The nucleoside reverse transcriptase inhibitor (NRTI) 4'-ethynyl-2-fluoro-2'-deoxyadenosine (EFdA) in preclinical development exhibits improved safety and antiviral activity profiles with minimal drug resistance compared to approved NRTIs. However, the systemic antiviral effica...

Descripción completa

Detalles Bibliográficos
Autores principales: Shanmugasundaram, Uma, Kovarova, Martina, Ho, Phong T., Schramm, Nathaniel, Wahl, Angela, Parniak, Michael A., Garcia, J. Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954669/
https://www.ncbi.nlm.nih.gov/pubmed/27438728
http://dx.doi.org/10.1371/journal.pone.0159517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954669/
https://www.ncbi.nlm.nih.gov/pubmed/27438728
http://dx.doi.org/10.1371/journal.pone.0159517

Ejemplares similares