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Efficient Inhibition of HIV Replication in the Gastrointestinal and Female Reproductive Tracts of Humanized BLT Mice by EFdA

BACKGROUND: The nucleoside reverse transcriptase inhibitor (NRTI) 4'-ethynyl-2-fluoro-2'-deoxyadenosine (EFdA) in preclinical development exhibits improved safety and antiviral activity profiles with minimal drug resistance compared to approved NRTIs. However, the systemic antiviral effica...

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Detalles Bibliográficos
Autores principales:	Shanmugasundaram, Uma, Kovarova, Martina, Ho, Phong T., Schramm, Nathaniel, Wahl, Angela, Parniak, Michael A., Garcia, J. Victor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954669/ https://www.ncbi.nlm.nih.gov/pubmed/27438728 http://dx.doi.org/10.1371/journal.pone.0159517

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