Tyrosine Phosphorylation of SGEF Regulates RhoG Activity and Cell Migration

SGEF and Ephexin4 are members of the Ephexin subfamily of RhoGEFs that specifically activate the small GTPase RhoG. It is reported that Ephexin1 and Ephexin5, two well-characterized Ephexin subfamily RhoGEFs, are tyrosine-phosphorylated by Src, and that their phosphorylation affect their activities...

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Detalles Bibliográficos
Autores principales: Okuyama, Yusuke, Umeda, Kentaro, Negishi, Manabu, Katoh, Hironori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954681/
https://www.ncbi.nlm.nih.gov/pubmed/27437949
http://dx.doi.org/10.1371/journal.pone.0159617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954681/
https://www.ncbi.nlm.nih.gov/pubmed/27437949
http://dx.doi.org/10.1371/journal.pone.0159617

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