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Tadalafil Promotes the Recovery of Peripheral Neuropathy in Type II Diabetic Mice

We previously demonstrated that treatment of diabetic peripheral neuropathy with the short (4 hours) half-life phosphodiesterase 5 (PDE5) inhibitor, sildenafil, improved functional outcome in diabetic db/db mice. To further examine the effect of PDE5 inhibition on diabetic peripheral neuropathy, we...

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Detalles Bibliográficos
Autores principales: Wang, Lei, Chopp, Michael, Szalad, Alexandra, Lu, XueRong, Jia, LongFei, Lu, Mei, Zhang, Rui Lan, Zhang, Zheng Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954704/
https://www.ncbi.nlm.nih.gov/pubmed/27438594
http://dx.doi.org/10.1371/journal.pone.0159665