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PF-05231023, a long-acting FGF21 analogue, decreases body weight by reduction of food intake in non-human primates

PF-05231023, a long-acting FGF21 analogue, is a promising potential pharmacotherapy for the treatment of obesity and associated comorbidities. Previous studies have shown the potential of FGF21 and FGF21-like compounds to decrease body weight in mice, non-human primates, and humans; the precise mech...

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Detalles Bibliográficos
Autores principales: Thompson, W. Clayton, Zhou, Yingjiang, Talukdar, Saswata, Musante, Cynthia J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954843/
https://www.ncbi.nlm.nih.gov/pubmed/27405817
http://dx.doi.org/10.1007/s10928-016-9481-1