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Capillary-induced Homogenization of Matrix in Paper: A Powerful Approach for the Quantification of Active Pharmaceutical Ingredients Using Mass Spectrometry Imaging

Herein we present a novel approach for the quantification of active pharmaceutical ingredients (APIs) using mass spectrometry imaging. This strategy uses a filter paper previously “eluted” with a MALDI matrix solution as a support for analyte application. Samples are submitted to mass spectrometry i...

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Detalles Bibliográficos
Autores principales: de Menezes, Maico, de Oliveira, Diogo Noin, Catharino, Rodrigo Ramos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954946/
https://www.ncbi.nlm.nih.gov/pubmed/27439589
http://dx.doi.org/10.1038/srep29970