TALE-directed local modulation of H3K9 methylation shapes exon recognition

In search for the function of local chromatin environment on pre-mRNA processing we established a new tool, which allows for the modification of chromatin using a targeted approach. Using Transcription Activator-Like Effector domains fused to histone modifying enzymes (TALE-HME), we show locally res...

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Detalles Bibliográficos
Autores principales: Bieberstein, Nicole I., Kozáková, Eva, Huranová, Martina, Thakur, Prasoon K., Krchňáková, Zuzana, Krausová, Michaela, Oesterreich, Fernando Carrillo, Staněk, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954949/
https://www.ncbi.nlm.nih.gov/pubmed/27439481
http://dx.doi.org/10.1038/srep29961

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954949/
https://www.ncbi.nlm.nih.gov/pubmed/27439481
http://dx.doi.org/10.1038/srep29961

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