A novel, rapid method to compare the therapeutic windows of oral anticoagulants using the Hill coefficient

A central challenge in designing and administering effective anticoagulants is achieving the proper therapeutic window and dosage for each patient. The Hill coefficient, n(H), which measures the steepness of a dose-response relationship, may be a useful gauge of this therapeutic window. We sought to...

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Detalles Bibliográficos
Autores principales: Chang, Jeremy B., Quinnies, Kayla M., Realubit, Ronald, Karan, Charles, Rand, Jacob H., Tatonetti, Nicholas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954953/
https://www.ncbi.nlm.nih.gov/pubmed/27439480
http://dx.doi.org/10.1038/srep29387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954953/
https://www.ncbi.nlm.nih.gov/pubmed/27439480
http://dx.doi.org/10.1038/srep29387

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