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A novel, rapid method to compare the therapeutic windows of oral anticoagulants using the Hill coefficient
A central challenge in designing and administering effective anticoagulants is achieving the proper therapeutic window and dosage for each patient. The Hill coefficient, n(H), which measures the steepness of a dose-response relationship, may be a useful gauge of this therapeutic window. We sought to...
Autores principales: | Chang, Jeremy B., Quinnies, Kayla M., Realubit, Ronald, Karan, Charles, Rand, Jacob H., Tatonetti, Nicholas P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954953/ https://www.ncbi.nlm.nih.gov/pubmed/27439480 http://dx.doi.org/10.1038/srep29387 |
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