Cargando…
MicroRNA-mediated target mRNA cleavage and 3′-uridylation in human cells
MicroRNAs (miRNAs) play an important role in targeted gene silencing by facilitating posttranscriptional and translational repression. However, the precise mechanism of mammalian miRNA-mediated gene silencing remains to be elucidated. Here, we used a stem-loop array reverse-transcription polymerase...
Autores principales: | Xu, Kai, Lin, Jing, Zandi, Roza, Roth, Jack A., Ji, Lin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954961/ https://www.ncbi.nlm.nih.gov/pubmed/27440378 http://dx.doi.org/10.1038/srep30242 |
Ejemplares similares
-
Detection of siRNA-mediated target mRNA cleavage activities in human cells by a novel stem-loop array RT-PCR analysis
por: Lin, Jing, et al.
Publicado: (2016) -
Zcchc11-dependent uridylation of microRNA directs cytokine expression
por: Jones, Matthew R., et al.
Publicado: (2009) -
Uridylation of RNA Hairpins by Tailor Confines the Emergence of MicroRNAs in Drosophila
por: Reimão-Pinto, Madalena M., et al.
Publicado: (2015) -
Selective microRNA uridylation by Zcchc6 (TUT7) and Zcchc11 (TUT4)
por: Thornton, James E., et al.
Publicado: (2014) -
3′ uridylation precedes decapping in a novel pathway of bulk mRNA turnover
por: Rissland, Olivia S., et al.
Publicado: (2009)