Fusion of the mouse IgG1 Fc domain to the VHH fragment (ARP1) enhances protection in a mouse model of rotavirus

A variable fragment of a heavy chain antibody (VHH) directed against rotavirus, also referred to as anti-rotavirus protein 1 (ARP1), was shown to confer protection against rotavirus induced diarrhea in infant mouse model of rotavirus induced diarrhea. In this study, we have fused the mouse IgG1 Fc t...

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Detalles Bibliográficos
Autores principales: Günaydın, Gökçe, Yu, Shengze, Gräslund, Torbjörn, Hammarström, Lennart, Marcotte, Harold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954977/
https://www.ncbi.nlm.nih.gov/pubmed/27439689
http://dx.doi.org/10.1038/srep30171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954977/
https://www.ncbi.nlm.nih.gov/pubmed/27439689
http://dx.doi.org/10.1038/srep30171

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