The Molecular Mechanism of Opening the Helix Bundle Crossing (HBC) Gate of a Kir Channel

Inwardly rectifying K(+) (Kir) channels, serving as natural molecular nanomachines, transport potassium ions across the plasma membrane of the cell. Along the ion permeation pathway, three relatively narrow regions (the selectivity filter (SF), the inner helix bundle crossing (HBC), and the cytosoli...

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Detalles Bibliográficos
Autores principales: Meng, Xuan-Yu, Liu, Shengtang, Cui, Meng, Zhou, Ruhong, Logothetis, Diomedes E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954981/
https://www.ncbi.nlm.nih.gov/pubmed/27439597
http://dx.doi.org/10.1038/srep29399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954981/
https://www.ncbi.nlm.nih.gov/pubmed/27439597
http://dx.doi.org/10.1038/srep29399

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