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The Molecular Mechanism of Opening the Helix Bundle Crossing (HBC) Gate of a Kir Channel
Inwardly rectifying K(+) (Kir) channels, serving as natural molecular nanomachines, transport potassium ions across the plasma membrane of the cell. Along the ion permeation pathway, three relatively narrow regions (the selectivity filter (SF), the inner helix bundle crossing (HBC), and the cytosoli...
Autores principales: | Meng, Xuan-Yu, Liu, Shengtang, Cui, Meng, Zhou, Ruhong, Logothetis, Diomedes E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954981/ https://www.ncbi.nlm.nih.gov/pubmed/27439597 http://dx.doi.org/10.1038/srep29399 |
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