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Non-invasive evaluation of neuroprotective drug candidates for cerebral infarction by PET imaging of mitochondrial complex-I activity

The development of a diagnostic technology that can accurately determine the pathological progression of ischemic stroke and evaluate the therapeutic effects of cerebroprotective agents has been desired. We previously developed a novel PET probe, 2-tert-butyl-4-chloro-5-{6-[2-(2-(18)F-fluoroethoxy)-...

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Detalles Bibliográficos
Autores principales: Fukuta, Tatsuya, Asai, Tomohiro, Ishii, Takayuki, Koide, Hiroyuki, Kiyokawa, Chiaki, Hashimoto, Masahiro, Kikuchi, Takashi, Shimizu, Kosuke, Harada, Norihiro, Tsukada, Hideo, Oku, Naoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954989/
https://www.ncbi.nlm.nih.gov/pubmed/27440054
http://dx.doi.org/10.1038/srep30127