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Non-invasive evaluation of neuroprotective drug candidates for cerebral infarction by PET imaging of mitochondrial complex-I activity
The development of a diagnostic technology that can accurately determine the pathological progression of ischemic stroke and evaluate the therapeutic effects of cerebroprotective agents has been desired. We previously developed a novel PET probe, 2-tert-butyl-4-chloro-5-{6-[2-(2-(18)F-fluoroethoxy)-...
Autores principales: | Fukuta, Tatsuya, Asai, Tomohiro, Ishii, Takayuki, Koide, Hiroyuki, Kiyokawa, Chiaki, Hashimoto, Masahiro, Kikuchi, Takashi, Shimizu, Kosuke, Harada, Norihiro, Tsukada, Hideo, Oku, Naoto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954989/ https://www.ncbi.nlm.nih.gov/pubmed/27440054 http://dx.doi.org/10.1038/srep30127 |
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