Cell-Specific Promoters Enable Lipid-Based Nanoparticles to Deliver Genes to Specific Cells of the Retina In Vivo

Non-viral vectors, such as lipid-based nanoparticles (liposome-protamine-DNA complex [LPD]), could be used to deliver a functional gene to the retina to correct visual function and treat blindness. However, one of the limitations of LPD is the lack of cell specificity, as the retina is composed of s...

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Detalles Bibliográficos
Autores principales: Wang, Yuhong, Rajala, Ammaji, Cao, Binrui, Ranjo-Bishop, Michelle, Agbaga, Martin-Paul, Mao, Chuanbin, Rajala, Raju V.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955052/
https://www.ncbi.nlm.nih.gov/pubmed/27446487
http://dx.doi.org/10.7150/thno.15230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955052/
https://www.ncbi.nlm.nih.gov/pubmed/27446487
http://dx.doi.org/10.7150/thno.15230

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