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Cell-Specific Promoters Enable Lipid-Based Nanoparticles to Deliver Genes to Specific Cells of the Retina In Vivo
Non-viral vectors, such as lipid-based nanoparticles (liposome-protamine-DNA complex [LPD]), could be used to deliver a functional gene to the retina to correct visual function and treat blindness. However, one of the limitations of LPD is the lack of cell specificity, as the retina is composed of s...
Autores principales: | Wang, Yuhong, Rajala, Ammaji, Cao, Binrui, Ranjo-Bishop, Michelle, Agbaga, Martin-Paul, Mao, Chuanbin, Rajala, Raju V.S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955052/ https://www.ncbi.nlm.nih.gov/pubmed/27446487 http://dx.doi.org/10.7150/thno.15230 |
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